Saturday, July 2, 2011

KAUTI/GOUT PART 2

HOW DO I KNOW IF I HAVE GOUT?
“Ko e kauti ena!” or “Na’e pehena pe kamata e langa hoku kauti!”  These are normally the diagnostic remarks that we Tongans give when someone starts complaining of pain in the foot, or when we see someone limping!  There’s an inner diagnostician/clinician in everyone but it seems more pronounce in our Tongan community. 
If you grew up in Tonga, or spent some time there as a child, or even have your grandmas or aunts live by you here in the states, then you know exactly what I’m talking about.  “Ko e pala ena ia!”  “Ai o fk-inu ha’a ne vaipala”  “Omai keu mili’I pe tolotolo’I ‘aki ha me’I lolo”.   “Mahalo na’e taa’I ena ha tevolo koe lahi ho’o mou vainga mo halaloto’api he mala’e!” (Yes we are very superstitious too!).
If you have never drink ‘vaipala’ before, consider yourself one lucky SOP (son of privilege)!  That stuff is straight up nasty!  If you don’t know what ‘vaipala’ is, don’t ask your mom, aunt, or grandma…it might give them ideas.  Ok ok…I’ll stay focused and get back to the topic in discussionJ.
Gout is almost always acute…meaning that it comes on suddenly.  We often hear “Ko ‘ene ‘aa hake he pongipongi, ikai lava o tu’u he langa e va’e”.  That’s the most practical Tongan definition of acute.  It often happens without warning at night and it is painful…at least that’s what patients say…don’t accuse me of having gout…and even if I do, I will never admit to it…mhk! 
Within the first 12-24 hours, the pain is intense and most severe.  When a patient is asked to describe the pain, they often use words like “sharp”, “poking”, “stabbing”, and other related adjectives.  As mentioned on the first part, it almost always first appears on the large joint of the big toe.  Medically, this joint is called the first MTPJ (metatarsal phalange) joint.  The pain may last from a few days to a few weeks.  We often hear “Kuo toe kovi aupito hono kauti ona he taimi ni.  Koe kamakamata na’e aho pe fia pea sai.  Taimi ni ia, oku laulau aho ia”.  Recurrent gouty attacks will last longer than before and it happens more often.  This is called CHRONIC gout attack.
The affected area are normally swollen (ki’I fufula), red (kulokula), and tender (mohomoho…I think that’s the right word!).
If you find all of the bold and yellow words and phrases next time your husband, boyfriend (in which case you should turn and run the opposite direction….koe loi pe ia…haha), dad, or brother complains of pain in their foot, you can with confident diagnose them with gouty arthritis/kauti.  Too bad, we can’t prescribe ‘vaipala’ for it!  (At least I am not aware of…lol)

TREATMENTS
Shortly after I posted on facebook that I started a medical information blog for my fellow Tongans, one of my FB friends, Lani Saia Moleni posted “Koe kauti koe folo’I pe fo’I’akau pe a lava ai pe.”  There’s some truth and some dangers to this notion.  There are pills (fo’I’akau) for gout out there.  Here’s a list:


·       Allopurinol (Zyloprim)
·       Anturane (Sulfinpyrazone)
·       ColBenemid (Proben-C)
·       Colchicine
·       Fenofibrate (Tricor)
·       Losartan (Cozaar, Hyzaar)
·       Corticosteroids
·       Probenecid (Benemid)
·       Uloric (Febuxostat)- experimental

This is the point of the reading where you go get your dad’s, brother’s, husband’s, grandpa’s, boyfriend’s, and even yours gout medication to see which one they are using. 
To save you from all the biochemical jargons, I am not gonna discuss each drug individually.  (If you want more info, click on the appropriate link to the right of this).  The general aim behind all of these drugs is to lower the uric acid level in the blood, break up the crystals that are already formed, and/or prevent the formation of the crystals.
Some of you may wonder how come I don’t have IBUPROFEN (ADVIL) and ALEVE (NAPROXEN) listed above.  A lot of our people take these when their kauti is langa and it seems to help.  These are categorized as Nonsteroidal anti-inflammatory drugs (NSAIDs).  They only “treat” the inflammation ~ kulokula, fufula, mohomoho, and langa but they DON’T treat gout. 
As magical as many of these medications are, we need to remember that they have serious side effects, potential drug interactions (if you are taking medications for other issues), and are also very costly!
This is crucial to understand and remember because you can ‘folo fo’I’akau’ all you want but unless lifestyle and diet changes, then the underlying problem will never be appropriately dealt with.  There’s no ‘magic pill’ for gout.  Each one of these medications will lose its potency and effectiveness if the individual doesn’t invest in fighting gout on a personal level.
I am currently not aware of any natural remedy, at least ones that are scientifically proven, that can relieve gouty attack.  However, I am aware of at least one clinical approach that relieves the pain instantly but is not usually done, let along offered by most clinicians.
A few months back, an expert in Gout spoke to us about doing a Posterior Tibial Injection with local anesthetic to a gout patient.  According to him, this injection does a few crucial thinks.  First, it will numb the patient to the pain. Second, it will increase the temperature in the area, and third, it will increase the pH or decrease the acidity of the local area.  If you remember from the first segment, crystals form due to drop in temperature and drop in pH (high acidity).  This posterior tibial injection reverses both of those and therefore combats the formation of uric acid crystals which therefore alleviate the inflammation and the pain.  So next time you see a clinician for gout, ask about this procedure.  It may set you back a few hundred bucks but it will be worth it.  Plus, you probably would have spent it at your favorite Chinese Buffet anyways…lol…me’a koe kau noa ee…

TAKEHOME MESSAGES
My point here is two-fold.  First, if we are not gonna go to a clinic and attempt to diagnose it at home, then we must know the definite clinical presentations of gout so we can diagnose it correctly.  There are other arthritic conditions that may manifest similar to gout such as pseudogout, arthritis, tendonitis, bursitis, and others.  The danger of wrong diagnosis is that we are helpful people.  We tend to say when someone is ketu-ing, “Mahalo koe kauti ena ia.  Atu e fo’I akau kauti mei api keke folo”. 
Fo’I’akau like allopurinol aka Lopurin, Zyloprim has been known to cause gout.  Can you imagine getting gouty attack/kauti because you took the wrong pills because of a wrong diagnosis?  Scary! Right?  Now, that’s just the minor deal.  We haven’t talked about kidney stones and other kidney related diseases yet!  So, stop taking kauti medication, unless it’s ibuprofen and other NSAIDs, without proper diagnosis.
Second, we need to get rid of the mentality “Kai koe kae toki folo ha fo’I ‘akau”.  I can’t even keep track of many times I’ve heard that at a wedding, family reunion, graduation party, and in buffets.  It always seems encouraging and comforting to the ‘kauti’ person.  This phrase never fails to draw unison laughter.  But this is NOT the only thing this phrase fails to bring.  It always brings pain, discomfort, extra expenses, financial problems, and family problems.  There is no magical pill.  What works now won’t alleviate the pain from gout next month if you continue down the same path.  It has been said that INSANITY is doing the same thing over and over again while expecting the different result.  In that case, “Kai koe kae toki folo ha foi’akau” is an extreme vocalization of insanity!

WE ARE NOT A GENETICALLY DEFECTED PEOPLE!

SURVIVAL OF THE FITTEST
There’s a saying in the circle of Geneticists “Survival of the Fittest” that most, if not all of us have heard before.  I have heard it being used repeatedly on Reality TV shows, sports, in the work place, and even here on facebook.  I‘ve noticed that almost 99.99% of the time, it is being used incorrectly.  It is often used as a declaration of dominance over another.  Normally, I hear it being used when one is flexing his/her physical, mental, and even good look muscles. 
However, such implication is a little misconstrued.  “Survival of the Fittest” refers to those that are MOST able to pass on their genetic information via offsprings.  In which case, it’s not always the most physical dominant, the best looking, or the brightest that are most able to pass on their genetic information.  Sometimes, it is the opposite, or most times it is a combination of these and little bit of luck. If you have looked at a couple and mentally wondered “Masi’I, na’e anga fefe e to ‘a e ki’I fefine he masi’I ko eni? Then you have witnessed what I am talking about.  Our Tongan ancestors understood this clearly and that’s why we have such sayings “Kapau ‘oku kovi e mata, pea ‘ai a e anga ke sia’a” or “Ai e setesi ke koula” or “Fena pe ka ko Nua”.  You guys know what I’m talking about…I won't mention names...MHK!
Most times, it is those that have experienced some sort of genetic mutations that allow them to function without hindrance under stressful conditions that are able to be the SURVIVOR OF THE FITTEST!

“API FA’A TOE TU’U AI E TEVE”
My purpose for opening with such discussion above is to dispel any misconceptions (I’m not saying that there’s any) that my last post may have suggested that we, Polynesians, are genetically DEFECTED since studies have shown that we have some sort of genetic mutation(s) that lead to high level of uric acid in our blood (pheww…such a long sentence….forgive my FOBiness).
We can suspect that such mutation(s) was beneficial and perhaps necessary to our ancestors considering their living conditions and circumstances.  It allowed our ancestors to squeeze every little ounce out of whatever meats they consumed or allowed for less secretion and higher chance of metabolizing molecules for energy.  There’s no actual scientific data to back my presumption.  However, a similar presumption has been documented for why the Native Americans tend to have high sugar level in their blood.  That led to the coining of the term “Hunter/Gatherer Genes”.
There’s a Tongan proverbs that says “Api fa’a, toe tu’u ai e Teve”.  Api means home, estate, or in this case, a farm.  Fa’a refers to being abundant...most likely with food, normally referring the place of a fruitful farmer.  Teve, was a type of food that was only eaten when there were absolutely nothing else to eat.  Perhaps it was unpleasant and hard to ‘stomach’.  (Sorry, I have never tried it, let along seen it).  So, the proverb basically means to be prepared. 
With that in mind, perhaps we can say that such mutation(s) left us with some ‘Api fa’a toe tu’u ai e Teve’ GENES.  I guess we can LITERALLY say that being prepared is IN OUR GENES!!  I believe these genetic mutations played a great role in the survival of our ancestors and our being here today.  Those without where weeded out!

ONCE OUR ALLIES, NOW OUR ENEMY?
Change is the only thing that’s constant.  Time has change and the stresses and challenges that we face today are definitely different from those that our ancestors dealt with.  This ‘Api fa’a toe tu’u ai e Teve’ gene that perhaps once protected our ancestors may have become our demise.  Its role seems to change.  Since we can’t easily re-mutate these genes back or easily weed out those with it (unless your name is Adolf Hitler), we need to do everything we can to protect ourselves from…..ourselves!  Embracing who we are as a people also means having the ‘SURVIVE and PROSPER’ mentality as our ancestors did.  
Time, nature, and our forefathers did whatever they could to pass down their genetic information and now it is our turn to follow suit!  TONGA MA'A TONGA!